Publication

Gonçalves JW, Valiati VH, Delprat A, Valente VL, Ruiz A
BMC genomics (Volume: 15)
2014 Sep 15
PubMed: 252182...  | PMC: PMC41680...  | DOI: 10.1186/... 

Participating groups

Drosophila Evolutionary Genetics

Members

Abstract

Galileo is one of three members of the P superfamily of DNA transposons. It was originally discovered in Drosophila buzzatii, in which three segregating chromosomal inversions were shown to have been generated by ectopic recombination between Galileo copies. Subsequently, Galileo was identified in six of 12 sequenced Drosophila genomes, indicating its widespread distribution within this genus. Galileo is strikingly abundant in Drosophila willistoni, a neotropical species that is highly polymorphic for chromosomal inversions, suggesting a role for this transposon in the evolution of its genome.

We carried out a detailed characterization of all Galileo copies present in the D. willistoni genome. A total of 191 copies, including 133 with two terminal inverted repeats (TIRs), were class...